In the present study, we found that 1) the CSRP2BP expression was significantly increased in clinical cervical cancer tissues and cell lines, 2) CSRP2BP overexpression promoted tumour growth and metastasis in both vitro and vivo, 3) CSRP2BP knockdown significantly inhibited tumour growth and metastasis, and 4) clinically, elevated expression of CSRP2BP was significantly correlated with decreased overall survival rates. This evidence concerns the gene KAT14 and neoplasm.