Deletion of SBE2 in N-cadherin-Luc (SEBM-Luc) reporter significantly reduced SMAD4/CSRP2BP complex-increased N-cadherin promoter activity, supporting the idea that SMAD4 recruits CSRP2BP specifically to the SBE2 site of the N-cadherin promoter in cervical cancer cells (Fig. 6G, H). The gene discussed is SMAD4; the disease is cervical cancer.