The selected genes (CHST11, GLS, PPP1R12A) that are overexpressed in B/My and T/My MPAL blast cells in single-cell data, showed significantly higher expression (Wilcoxon rank test, p-value < 0.05) in MPAL versus T-ALL and AML bulk RNA-seq TARGET samples (Fig. 2E). This evidence concerns the gene GLS and acute lymphoblastic leukemia.