ANXA6 has been identified as a newly synthesized protein in starvation-induced autophagy, and is a novel autophagy regulator that regulates autophagosome formation, which can regulate autophagic by inhibiting the PI3K/AKT/mTOR pathway, thereby improving the therapeutic resistance of nasopharyngeal carcinoma to radiotherapy [16]. The gene discussed is AKT1; the disease is nasopharyngeal carcinoma.