The high expression of ABCB9, SPTBN2, GULP1, IGF1, P4HB, NES and DPYSL2 and the low expression of ANXA6, OAS1, RAD9a, DNASE2B and FANCF would be beneficial to the prognosis of bladder cancer patients. The gene discussed is SPTBN2; the disease is urinary bladder cancer.