CDKN2A and esophageal squamous cell carcinoma: The affiliation of the two SNPs changed into assessment with the aid of CDKN2A / B locus (rs1333049 and rs10811661) and the clinical manifestations of esophageal squamous cell carcinoma (ESCC) and counseled that the CC rs1333049 genotype was polymorphically associated with a weaker overall prognosis [39].