After 14 days of infection, there were 257 genes with greater expression in nociceptor-ablated mice (e.g., Vegfa, IL1a, IL1b, and Tnf) compared to 219 genes with greater expression in control mice (e.g., Alox5, Car2, Ccl5, Elane, and Mmp8) (Fig. 2B). The gene discussed is IL1B; the disease is infection.