RNF43 and colon adenocarcinoma: For example, RNF43 was employed for its high expression level in colon adenoma compared with normal tissue in PROTAB development18, and our analysis also highlighted RNF43 that was highly expressed in 2 TCGA tumor types, including Colon adenocarcinoma (COAD), and lowly expressed in all GTEx normal tissues, suggesting our analysis could also support the development of other related TPD fields.