Interestingly, the geometric mean frequencies of intact genomes at 60 wk post-infection (1,013 copies per million CD4+ T cells) and at 89 wk post-infection (1,279 copies per million CD4+ T cells) were not significantly different (P = 0.43), consistent with a relatively stable set point level of infected cells in untreated infection (Fig. 2C). This evidence concerns the gene CD4 and infection.