LPAR1 and cancer: Moreover, the aberrant expressionof LPAR1 was reported in primary cancer cells across multiple organs,21 including ovaries,22 liver,23,24 stomach,25 pancreas,26,27 lungs,24,28 brain (glioblastoma),29−31 and bones.32 Recent studies reported that silencing18 or knocking out LPAR133 inhibited cancer metastasis.