In both in vitro and in vivo experiments, rNDV or rNDV‐TRAIL infection activated BAX production and deactivated Bcl‐2 production, particularly evident in the BAX/Bcl‐2 ratio, which exhibited a more substantial increase in HT‐29 cells compared to HCT116 cells (Figure 3A and 5A). Here, BAX is linked to infection.