Other than identifying well-known variants within GBA, our GWAS analysis also identified several novel and significant variants and gene loci; among these, three novel intron variants in LMNA (p-values smaller than 4.0e-21) and one novel missense variant in SEMA4A (p-value = 1.11e-26) with very small p-values are particularly interesting, since LMNA and semphorins were reported to be associated with PD by other studies. This evidence concerns the gene SEMA4A and Parkinson disease.