ATG16L1 and inflammatory bowel disease: In addition, many IBD-associated genetic variants implicate genes with immune function or influence host-microbiome interactions, such as NOD2 and ATG16L1.50 This indicates that, while we were unable to incorporate microbiome data in this study, microbiome data may provide additional information and adding microbiome data to the model may improve the prediction accuracy on subtypes of IBD.