In general, based on our study results, the correlation of neurochemicalchanges (measured with the selective 5-HT1A tracer[18F]MeFWAY) with the behavioral assessment was reasonable, with a bettercorrelation of neurochemical changes with anxiety-like or depressive-like behavior,and less so with mechanosensory pain threshold measurement. The gene discussed is HTR1A; the disease is Anxiety.