TLR8 and COVID-19: For example, PPP2R1A, NSMAF, S1PR5, FYN, PTEN, PPP2R5A, GNA13, and PLCB2 are involved in the ‘Sphingolipid signaling pathway’; RHOT1, BNIP3L, TAX1BP1, MFN1, and BCL2L1 are associated with ‘Mitophagy’; NDUFA4, NDUFB3, COX7A2, PPA2, UQCRQ, ATP6V1G1, and COX7B are related to the process of ‘Oxidative phosphorylation’; and, SPTAN1, PRF1, CTSW, CTSK, GZMB, and BCL2L1 are linked to ‘Apoptosis.’ Interestingly, some DEGs, such as RSL24D1, RPS15A, RPLP0, IRF3, RPL31, RPL23, RPL15, RPS27L, RPS4Y1, TLR8, and RPS24, are found to be associated with ‘Coronavirus disease - COVID-19’.