To this end, T cell ELISPOT assays for the detection of IFN-γ, IL-2, GzB and PFN were performed, showing significantly lower levels of IFN-γ and PFN secretion in MS patients (P = 0.0119 for IFN-γ; P = 0.0005 for PFN) (Figure 1A) compared to HCs. The gene discussed is IFNG; the disease is myeloid sarcoma.