The last of these studies in 2023, demonstrated a significant increase in the serum and CSF of IL-6 along with TNF-α, CXCL8/IL-8, CCL2, MIP-1α, and IL-12p70 pro-inflammatory cytokines/chemokines in patients with status epilepticus (SE) compared with patients without SE. This evidence concerns the gene CXCL8 and status epilepticus.