PD-1 and LAG-3 were widely expressed and co-expressed on DLBCL TILs (PD-1+ TILs, n = 68, 49.6%; LAG-3+ TILs, n = 65, 47.4%; and PD-1+LAG-3+ TILs, n = 45, 32.8%) (Figure 2C; Supplementary Tables 3, 4). This evidence concerns the gene LAG3 and diffuse large B-cell lymphoma.