In addition, KEGG pathway analysis shows significant changes in genes involved in the PI3K-Akt, cAMP, MAPK, Wnt, JAK-STAT, TLR, IL-17, TGF-β, and chemokine-related signaling pathways in DLBCL patients, suggesting significant alterations in multiple signaling transduction pathways in DLBCL patient cells. Here, AKT1 is linked to diffuse large B-cell lymphoma.