IL6 and tuberculosis: Coronavirus disease 2019 (COVID-19) co-infection with TB can cause a large number of inflammatory cell infiltration in the lung; further enhance the immune response of the injured site; produce excessive cytokines like IL-1, IL-6, IL-10, IL-18, and IFN-α; and promote cytokine storms that lead to multiple organ dysfunction, resulting in a higher risk of death than a single pathogen (87, 88).