FGG and neoplasm: As a risk factor in this prognostic model, FGG significantly inhibited the progression of LUSC tumor cells after knockdown and reduced the expression of dry marker genes and the infiltration level of M1 type macrophages, suggesting that FGG is a potential biomarker for independent poor prognosis of LUSC to identify LUSC patients with poor clinical outcomes and that it may play specific roles in dry maintenance and immune infiltration.