KEGG analysis revealed that the LUSC-specific DEGs were associated with melanogenesis, small-cell lung cancer, the PI3K-Akt axis, viral myocarditis, human papillomavirus infection, ECM-receptor association, the Rap1 signaling pathway, Staphylococcus aureus infection, and glutathione metabolism (Figure 2B). This evidence concerns the gene AKT1 and staphylococcus aureus infection.