METTL3 and acute kidney injury: It was found that METTL3 overexpression of m6A in cells decreases Foxd1 content and causes apoptosis (74); METTL3 overexpression also leads to an increase in tgf-β-activated kinase 1 binding protein 3 (TAB3), resulting in inflammation and cell injury (10); METTL14 overexpression causes a decrease in YAP1, leading to reduced cell viability and thus acute kidney injury (71).