In TGF-β1-treated tubular epithelial cells, m6A modification exerts a regulatory role in positively regulating MALAT1 expression by engaging METTL3, suggesting the involvement of m6A modification in the MALAT1/miR-145/focal adhesion kinase (FAK) pathway of renal fibrosis (92). Here, TGFB1 is linked to renal fibrosis.