Additionally, seven m6A markers [cell division cycle 5-like (CDC5L), cell division cycle 40(CDC40), heterogeneous nuclear ribonucleoprotein U (HNRNPU), nudix (nucleoside diphosphate linked moiety X)-type motif 21(NUDT21), poly(A) polymerase alpha(PAPOLA), polymerase (RNA) II (DNA directed) polypeptide B (POLR2B), and WW domain binding protein 4 (WBP4)] have been identified and implicated in the development and progression of LN. This evidence concerns the gene POLR2B and lobular neoplasia.