CCL2 and myocardial infarction: For example, in an experiment of a mouse model of myocardial infarction, Loyer et al. (65) found that exosomes with cytokines and growth factors (such as IL-6, chemokine ligands CCL2, and CCL7) were released by ischemic injured local myocardium and confirmed the same secretion phenomenon in human myocardial infarction.