Interestingly, one of these RIPs represents SVA_67, a truncated SVA element, which lies within the microtubule-associated protein tau (MAPT) locus on chromosome 17q21.31 (Figure 1B), a locus which has been shown to contribute to increased risk of PD and FTD (35, 36). The gene discussed is MAPT; the disease is frontotemporal dementia.