UBE2C and gastric cancer: To verify the effect of MYBL2 on drug resistance in GC cells, cells were subsequently treated with different concentrations of DDP (0, 5, 10, 20, 40, and 80 μM), and the results revealed that si-MYBL2 was able to significantly reduce the IC50 value of DDP in AGS cells, and the addition of oe-UBE2C could restore the IC50 value of cells to the si-NC + oe-NC group level (Figure 4f).