SLC5A2 and type 2 diabetes mellitus: In a study by Hussain et al. [42] which aimed to compare the effect of dapagliflozin and empagliflozin on SUA level of T2DM patients against the traditional oral antihyperglycemic drugs after four weeks of medication, the mean SUA level of SGLT2 inhibitors group reduced from 7.5 ± 2.5 mg/dl to 6.3 ± 0.8 mg/dl, but the mean SUA level of the comparison group reduced from 7.1 ± 1.8 mg/dl to 6.8 ± 2.2 mg/dl.