Ser, serine; Thr, threonine; Tyr, tyrosine; c-Src, cellular tyrosine-protein kinase Src; CK2, casein protein kinase 2; cPKC, conventional protein kinase C; nPKC, novel protein kinase C; aPKC, atypical protein kinase C; VEGF, vascular endothelial growth factor; ROCK, Rho-associated protein kinase; MDCK, Madin Darby canine kidney cells; Caco-2, human colorectal epithelial adenocarcinoma cells; T84, human colon carcinoma cells; BMEC, brain microvascular endothelial cell; BREC, regulatory B cell; COS-7, African green monkey kidney cells (SV40 transformed). The gene discussed is SRC; the disease is colon carcinoma.