TP53 and posterior cortical atrophy: However, the cohort analyzed comprised only 60 PCa patients30 and these were not grouped according to the outcome of RT (recurrence/ no recurrence).30 Conversely, in 2002, Ritter et al. demonstrated that higher p53 indexes in pre-treatment biopsies significantly correlated with higher rates of PSA (biochemical) failure.31 Likewise, in our cohort, patients with higher p53 immuno-score displayed shorter recurrence-free survival in response to RT.