TP53 and posterior cortical atrophy: Furthermore, KDM6B only co-precipitated with p53 in 22Rv1-RR cells, strengthening the hypothesis that these two proteins are co-players in PCa cells’ response to IR-induced injury, which is in line with published data.18 Investigation of such epigenetic alterations holds the promise of identifying clinically helpful targetable molecules to improve RT response rates of PCa patients.