In individuals without increased CIMT, the rs2069827 polymorphism was associated with low risks of central obesity, hypoalphalipoproteinemia, and a low risk of presenting with high levels of total cholesterol (TC), non-high-density lipoprotein cholesterol (non-HDL-C), low-density lipoprotein cholesterol (LDL-C)/HDL-C index, apolipoprotein B, and gamma-glutamyl transpeptidase. The gene discussed is GGTLC1; the disease is hypoalphalipoproteinemia.