Furthermore, in clinical prostate cancer tissue, the IHC score of PTHrP increased with advanced T-stage (P ═ 0.034), and there was a significant positive correlation between the IHC scores of PTHrP and c-Met (r ═ 0.361, P < 0.001), as depicted in Figure 5E and 5G. Here, MET is linked to Familial prostate cancer.