The results demonstrated a positive correlation between PTHrP expression and several clinicopathological features, including initial PSA level (P ═ 0.026), pT stage (P ═ 0.001), lymph node metastasis (P ═ 0.010), distant metastasis (P ═ 0.004), and Gleason score (P ═ 0.026). Here, KLK3 is linked to metastatic malignant neoplasm in the lymph nodes.