Moreover, treatment of primary cultured microglia with FGF2 enhanced the phagocytosis of Aβ, and infection of primary cultured neurons with AAV2/1-FGF2 reduced the production of Aβ, indicating that FGF2 not only had an effective effect on neurons but also had effective phagocytosis of microglia56. This evidence concerns the gene FGF2 and infection.