Post-mortem analyses of AD patients’ cerebral cortices have shown that oxidative stress resulting from NOX2 activation plays a significant role in the development of AD (Hou et al., 2020; Ma et al., 2017; Rastogi et al., 2016; Sorce et al., 2017; Tarafdar and Pula, 2018). This evidence concerns the gene CYBB and Alzheimer disease.