BID and lymphoma: In these lymphoma cells, high levels of O-GlcNAc and Bortezomib lead to the accumulation of truncated BH3 Interacting Domain Death Agonist (Bid), a pro-apoptotic protein of the Bcl2 family, the level of which is further increased by direct O-GlcNAcylation, and ultimately results in apoptosis (134).