The CNA profiles were similar between the NF1-associated and sporadic tumours, although there was a trend towards a higher burden of CNAs (P = 0.07), LOH (P = 0.05, both from Wilcoxon's test), and homozygous deletion of CDKN2A (OR = 2.4, P = 0.06 from Fisher's exact test) in NF1-associated tumours (Supplementary Fig. S6). Here, CDKN2A is linked to neoplasm.