While the results of our univariate analysis showed that TMN stage (HR = 16.939, p = 0.0068), metastasis (HR = 9.971, p = 0.0030), and SSH1 expression Q-score (HR = 9.854, p = 0.0006) were strongly associated with HCC - related deaths, multivariate analysis revealed that only high SSH1 protein expression level is an independent predictor of disease-related death (HR = 7.272, p = 0.0042) (Table 1). Here, SSH1 is linked to hepatocellular carcinoma.