Trying to establish novel sepsis markers with a potential predictive value regarding organ dysfunctions as well, during the past few years, our research group has found non-commercially available complementary laboratory tests [10,14,15,16,17,18,19,20,21,22] and adapted most of them to automated laboratory instrumentation including serum gelsolin (GSN), Gc-globulin (Gc), presepsin/GSN ratio, and urinary markers such as orosomucoid (u-ORM), Cystatin C (u-CysC) and neutrophil gelatinase associated lipocalin (u-NGAL). Here, LCN2 is linked to Sepsis.