HPGDS and cancer: The differential gene expression levels relate, for example, to the Alpha-, Mu-, and Pi-classes of GSTs (GSTA, GSTM, and GSTP, respectively), which are present at high levels in many human solid cancers (e.g., pancreatic, colorectal, breast, and bladder cancers) and have been indicated in many reports to be overexpressed in a wide range of sensitive and resistant cancer cells [15,16,17,18].