CASP3 and cancer: →Hydroxytyrosol and ligstroside share antioxidant and anti-inflammatory properties. These compounds can influence apoptosis and gene regulation, helping to prevent the proliferation of cancer cells. Oleocanthal induces apoptosis in vitro due to increased caspase-3 and polyadenosine diphosphate-ribose polymerase, phosphorylation of p53 (Ser15)] and DNA alteration.