It also increased the content of SCFAs in faeces, restored the levels of MTL and VIP, and downregulated the levels of the pro-inflammatory cytokines IL-6 and IL-8 in the serum, thus repairing the inflammatory response caused by constipation, promoting peristalsis of the gastrointestinal tract, increasing the water content in faeces, and relieving constipation. Here, IL6 is linked to constipation disorder.