In this analysis, we confirmed proper protein distribution in intestinal epithelia (Figure 4C), but no relevant changes were found in gene expression (Table 3), suggesting that cellular differentiation of enterocytes in SBS patients was appropriate according to CK20-expression under both conditions, teduglutide-naïve and treated SBS patients. Here, KRT20 is linked to macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss.