Chemokines, such as CXCL-1 and MIP2 (CXCL-2), are major neutrophil chemoattractants that are produced in the lung in an airway inflammation model induced by DEP exposure; an increase in the pulmonary expression of these C-X-C chemokines exacerbated airway inflammation [25]. This evidence concerns the gene CXCL2 and inflammation.