In this sense, the Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is of interest due to its pleiotropic nature and its cytoprotective effects as a consequence of the activation of genes with antioxidant function, but it can also lead to the appearance, progression, and survival of cancer cells if they are hyperactivated, as has been observed in several types of cancer [26,27,28,29]. Here, NFE2L2 is linked to cancer.