ALB and brain cancer: Considering the benefits of using albumin as a drug delivery system and the fact that there are only two clinical trials (phase 1 and 2) for the treatment of glioblastoma using these delivery systems, we believe that this literature synthesis could help researchers in the field to develop new drug delivery systems based on albumin with improved properties to overcome the biological barriers that limit CNS drug delivery and aid in the early diagnosis and treatment of brain cancer.