CD274 and neoplasm: Specifically, the immune composition of tumor infiltrating lymphocytes (TILs), macrophages, programmed cell death protein-1 and -2 receptors (PDL-1 and -2) and the glial fibrillary acid protein (GFAP) were assessed, and it was found that the expression of PDL-1 on tumor-infiltrating lymphocytes positively correlated with overall survival [6].