Overall, the postoperative mean concentrations of CXCL-8 in groups A and C of PC patients were significantly increased compared to the preoperative ones, while a significant decrease was observed among patients of group B. Remarkably, the lowest postoperative level of CXCL-8 (26.5 ± 2.0 pg/mL) was observed in one of the patients of group A (patient no. 10) who lived for more than 180 days (Table 3). This evidence concerns the gene CXCL8 and pachyonychia congenita.