A GWAS reported an association between the major allele of the UMOD SNP rs4293393 (linked with higher uromodulin expression) and a decreased risk of kidney stone formation (OR: 0.88; 95% CI: 0.81–0.96; p = 0.0053) [25], which was also supported by the findings of Patel et al. [224]. This evidence concerns the gene UMOD and nephrolithiasis.