KCNQ1 opposite-strand/antisense transcript 1(KCNQ1OT1), a long non-coding RNA (lncRNA), was recognized as a miR-23b-3p sponge, and KCNQ1OT1 inhibition ameliorated DN by absorbing miR-23b-3p and regulating SEMA3A [79]. This evidence concerns the gene SEMA3A and liver dysplastic nodule.