In addition, with the prolonged treatment of HepG2 cells with 20 μg/mL of the CXCL14 protein, the expression levels of pro-apoptotic genes BAK and BAX increased significantly, while the expression levels of tumor pro-proliferation genes HIF1A, mTOR and CDK1 decreased significantly (Figure 5). The gene discussed is CDK1; the disease is neoplasm.