CDH2 and neoplasm: Expressions of adhesion molecules that are characteristic of epithelial-type tumors (such as E-cadherin, occludin, and a-catenin) are thus decreased, while expressions of molecules specific to mesenchymal-type tumors (including vimentin, fibronectin, and N-cadherin) are upregulated [131], thus promoting the motility and invasiveness of tumor cells and allowing for the development of tumor cells that are more resistant to apoptosis.