RET and medullary thyroid gland carcinoma: Cebrian and colleagues reported that STOP+388bp G>A (c.*388G>A, rs3026782) was associated with an increased risk of MTC while non intronic RET A45A (c.135A>G, p.Ala45=, rs1800858, gnomAD allelic frequency 73.6%) was associated with a protective effect [111], but these results were not replicated in another study [134].