RET is a tyrosine kinase receptor [6] and plays a central role in MTC development, not only in hereditary MTCs but also in sporadic cases, in which somatic RET pathogenic variants have also been reported in aggressive forms and been shown to correlate with worse outcomes, suggesting the importance of RET signalling pathways in the pathogenesis of MTC [6]. Here, NTRK1 is linked to medullary thyroid gland carcinoma.