ZNF154 and cancer: In a ±1000-bp window surrounding the ZNF154 probe cg21790626 site, we evaluated methylation status in 11 CpG nucleotides present on the array (Figure 1a); however, ZNF154 at the position cg21790626, which we previously reported, showed the highest average difference in methylation beta values between tumor and normal samples across all 14 cancer types.