Taken together, this demonstrates a robust association of ITGAL, ITGAX, and TMEM119 with the major immunosuppressive immune cell types (MDSC, Treg, and macrophages) in LUAD and LUSC, suggesting a contribution of their reductions to taxifolin-derived inhibition of NSCLC pathogenesis. The gene discussed is ITGAX; the disease is non-small cell lung carcinoma.