For instance, the human homologous genes for the murine genes upregulated by taxifolin in LL2 tumors, including Prdx6, Magohb, Nucks1, Dcaf13, and Txn1, acted to facilitate the CTL-mediated killing of tumor cells, as shown by their negative T cell dysfunction values (Figure S4A). The gene discussed is PRDX6; the disease is neoplasm.