ITGAX and non-small cell lung carcinoma: In our analysis of the mechanisms underlying taxifolin’s inhibition of murine LL2 (Lewis lung carcinoma) cell-produced tumors, which models human NSCLC [35], we detected downregulation of Itgal, Itgax, and Tmem119 gene expression among more than 500 differentially expressed genes (DEGs) resulting from taxifolin treatment.