MAPK10 and neoplasm: Multivariate analysis confirmed that tumor localization and ARAF and MAPK10 mutations were independent predictive factors of reduced DFS (HR = 2.1; 95% CI: 1.1–4.0; p = 0.019; HR = 3.9; 95% CI: 1.2–13.1; p = 0.027; HR = 49; 95% CI: 9.8–244.1; p < 0.001) (Table 6).